Two United States Patents relating to Kratom Extract and specific alkaloids.

01 January 2018
Two United States Patents  relating to Kratom Extract and specific alkaloids.

Kratom (Milragynia speciosa korth) is recognized increasingly as a remedy for opioid Withdrawal by individuals Who self-treat chronic pain and/or generalized substance abuse. For example, opioid Withdrawal from an abrupt cessation of opiate abuse may be self-managed by using Kratom. Further, high-throughput molecular screening identi?ed that a major component of Kratom (i.e., for example, mitragyinine) displayed high binding a?inity at mu, delta and kappa opiate receptors. The present invention contemplates that Kratom extract may also be useful for the treatment of other addictive drugs besides opiate derivatives.

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 Here you can see the patent given to Takayama for 7-Hydroxymitragynine an indole alkaloid derivatives having opioid receptor agonistic effect, and therapeutic compositions and methods relating to the same.

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